Hypoglycemia is most common in young children. Patients with acute adrenal insufficiency (AI) or Addisonian crisis generally present with acute dehydration, hypotension, hypoglycemia, shock, altered mental status or sudden death. ![]() It primarily presents as an adrenal crisis which is life threatening and requires prompt therapeutic management including fluid resuscitation and stress dose hydrocortisone administration. ![]() The main presenting symptoms such as fatigue are non-specific, hence diagnosis is often delayed. It is a rare disease and is life threatening if untreated. Adrenal insufficiency is caused by either primary adrenal failure or by secondary causes involving impairment of the hypothalamic -pituitary -corticotropic axis. Thomas Addison initially described a syndrome of weakness and hyperpigmentation associated with adrenal gland destruction in 1855. ![]() Overview: What every practitioner needs to know Are you sure your patient has adrenal insufficiency? What are the typical findings for this disease?
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May 2023
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